Category Archives: BioGaia

BioGaia study: Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis

Did you know that BioGaia Prodentis is the world’s most studied probiotic for oral health? With over 20 published studies regarding the product’s active ingredient, Lactobacillus reuteri Prodentis, it is clear that BioGaia Prodentis certainly has the clinical evidence to back it up! Among the several studies is this one published in the Journal of Clinical Peridontology that explores the effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis. Check out a summary of the study with the infographic below!


Happy National Ice Cream Month! How can you defend against tooth decay that sugar can cause?

Chances are, you will rarely find someone who will turn down a cold ice cream cone; especially during a hot month like July. As National Ice Cream Month wraps up, I’m sure all of you sweet-treat fanatics are wondering: what is all that sugar doing to my teeth? As it turns out, satisfying your sweet tooth with a high sugar intake comes with its risks.

In fact, according to the World Health Organization (WHO), dietary sugar intake is the single most detrimental factor associated with tooth decay. The problem linked to dental caries is not limited to a few cavities here and there. As a matter of fact, dental caries is the most prevalent noncommunicable (chronic) disease the world is faced with. On a case-to-case basis, individuals suffering from extreme tooth decay can face intense pain and complications on a daily basis. Additionally, attempting to solve the problem of dental caries on an international scale can put overwhelming strain on healthcare budgets across the globe.1 As you can see, an epidemic like this can put stress on both individual cases and the population as a whole.

The evidence is clear: sugar is most definitely not beneficial for your pearly whites. But the question still remains, how exactly is sugar wreaking havoc on your teeth? An important piece to note is that sugar itself is not the only attacker at fault. The other enemy at play here is, you guessed it, harmful bacteria. These groups of bacteria seem to have a sweet tooth of their own – allow me to explain.

When you consume sugar, say in ice cream for example, bacteria begin to feed on the free sugars left behind. In doing so, plaque is formed on your teeth. If the plaque is left occupying the tooth surface for too long, the pH of the oral cavity begins to plummet. As the mouth becomes increasingly acidic, this eats away at your teeth, ultimately leading to cavities and tooth decay if not treated.2

This, of course, is not to say that all bacteria that can inhabit your mouth are destructive. In reality, there are good bacteria that can exist in the mouth that can play a role in actually defending against tooth decay. Without further ado, allow me to introduce the probiotic Lactobacillus reuteri. This beneficial bacterium is an all-star when it comes to promoting good oral health, including defense against tooth decay, with the scientific evidence to back it up.

A study published in the journal entitled Caries Research aimed to analyze the effect on caries in primary teeth after Lactobacillus reuteri supplementation. The study involved the participation of pregnant mothers during their final month of gestation and their children up until their first birthday. The group of 113 children were divided into a probiotic group involving 60 children and a placebo control group involving 53 children. These children were later assessed at 9 years of age to evaluate their oral health state. Interestingly, results showed that 82% of the children in the probiotic group were caries-free, while only 58% of the children in the placebo group were caries-free. This was despite no significant differences in oral hygiene habits and diet.3

I’m sure sugar enthusiasts will see these results as great news. A quick, easy and safe way to defend against tooth decay – yes please, hand it over! Luckily for those with a sweet tooth, BioGaia Prodentis harnessed the probiotic bacterium Lactobacillus reuteri into one, mint-flavoured lozenge. With these lozenges, it’s never easier to upgrade your oral health game. Who said you can’t have your ice cream and eat it too?

  1. Guideline: Sugars intake for adults and children. Geneva: World Health Organization; 2015.
  2. Tan, V. (2017). How sugar causes cavities and destroys your teeth.
  3. Stensson, M., Koch, G., Coric, S., Abrahamsson, T. R., Jenmalam, M. C., Birkhed, D., & Wendt, L. K. (2014). Oral administration of Lactobacillus reuteri during the first year of life reduces caries prevalent in the primary dentition at 9 years of age. Caries Research, 48(2), 111-117. doi: 10.1159/000354412

Lactobacillus reuteri: A different approach to periodontal therapy

Periodontitis is a battle between the host’s mouth and the harmful bacteria causing the damage. Despite there being two players in this situation, the emphasis of current periodontal treatment only focuses on one part of the equation. The main spotlight is held on the pathogenic bacteria, or periopathogens, while giving little attention to sensitivity of the host and lack of mouth microbiota balance.

Presently, the main means of tackling periodontitis involves a combination of scaling and root planing (SRP) in addition to keeping up with good oral hygiene practices. However, these methods come with their limitations. While SRP can significantly decrease the amount of periopathogens in the mouth, the solution poses to be short-lived as the bacteria begins to rapidly re-colonize. Although the suggestion of maintaining impeccable oral hygiene following SPR sounds promising, the re-establishment of that bacteria is inevitable. Even when good oral hygiene practices are followed and used in conjunction with antibiotics or antiseptics, the pathogenic bacteria continue to harbor within the mouth.

It is evident that we are faced with a problem. With the inescapable army of periopathogens continuing to wreak havoc on the oral environment, a different approach to treating periodontal disease could be refreshing. This roadblock has caused professionals within the dental field to think outside-the-box in terms of periodontal therapy. This is where the use of beneficial bacteria comes into the equation.

Rather than battling against the stubborn and relentless periopathogens, new research suggests an alternative technique – balancing the host’s oral environment. This can be achieved through the introduction of beneficial bacteria in the form of probiotics. Promoting a balance in the mouth not only reduces the host’s susceptibility to the damage caused by pathogenic bacteria, it also provides an abundance of additional benefits. Some of these benefits include reductions in plaque, halitosis and caries-related risk factors, to name a few.

This particular topic has had a lack of exploration until recent years. In 2013, a study published in The Journal of Clinical Periodontology decided it was time to investigate. The study focused on exploring the adjunctive use of Lactobacillus reuteri following SRP in adults with chronic periodontitis. The researchers hypothesized that the use of lozenges containing this beneficial bacterium would be more effective in the maintenance of periodontal disease as opposed to SRP treatment alone.

With a sample size of 30 chronic periodontitis patients, the individuals were randomized into 1 of 2 groups: one receiving SRP plus a placebo and the other receiving SRP plus a probiotic. Monitoring of each patient occurred at the beginning of the study and continued to weeks 3, 6, 9 and 12. After wrapping up the clinical trial at week 12, evaluations demonstrated promising results and conclusions. Compared to the placebo group, the cohort receiving the probiotic in conjunction to SRP treatment showed significant pocket depth reduction as well as lower Porphyromonas gingivalis numbers.

The results of this study hold valuable conclusions that can be used in the advancements of non-surgical periodontal therapy. The introduction of beneficial bacteria, Lactobacillus reuteri in particular, is what some may consider the future of oral health maintenance. BioGaia Prodentis lozenges make use of this excellent lactic acid bacterium to better the oral health of patients. With its minty flavour and tablet-like appearance, administration is both easy and convenient. Although this study focused on treating periodontitis, BioGaia Prodentis lozenges have been studied and shown to help treat multiple other oral health related risk factors. Whether it is reduction in plaque, gingivitis, halitosis, you name it, BioGaia is ready to solve your problem.


Teughels, W., Durukan, A., Ozcelik, O., Pauwels, M., Quirynen, M., & Haytac, M. C. (2013). Clinical and microbiological effect of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study. Journal of Clinical Periodontology, (40)11,1025-1035.