ARESTIN® (minocycline HCl) Microspheres 

A unique microsphere delivery system provides therapeutic levels of antibiotic1

Microsphere technology makes ARESTIN (minocycline HCl) Microspheres, 1 mg easy to use

ARESTIN allows for easy, targeted placement at the base of the periodontal pocket.1 Once inserted in the pocket, ARESTIN microspheres immediately adhere to the surrounding surfaces, providing a sustained release of minocycline at the site of active infection.1,2

ARESTIN is easy to use1

  • No premixing or premeasuring
  • No adhesive required
  • No need to remove ARESTIN after treatment (since the microspheres are completely bioresorbed)
  • No local anesthesia required
  • No dressing required
  • ARESTIN remains active in the pocket for an extended period of time2

ARESTIN is a locally applied antibiotic that is placed directly into the infected periodontal pocket at the time of scaling and root planing (SRP).1 ARESTIN has a unique delivery system where minocycline microspheres are administered as a powder to allow for easy, targeted placement at the base of the periodontal pocket.1

  • Data suggests no significant increase of minocycline-resistant bacteria1
  • Delivers a concentrated dose directly to the base of the pocket and the active infection site1
  • Convenience of an in-office treatment with no pills to take1
  • Allows for a variable dosing, as low as 1 mg per site1

1 mg of minocycline powder per cartridge


REFERENCES: 1. ARESTIN® (minocycline hydrochloride) Microspheres, 1 mg. Prescribing Information. OraPharma; Horsham, PA: 2015. 2. Williams RC, Paquette DW, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol. 2001;72(11):1535-1544. 


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