HANSAmed Geistlich Bio-Oss Pen

Geistlich Bio-Oss Pen®

1. When do you use the large Geistlich Bio-Oss Pen® particles (1-2 mm) and when do you use the small (0.25-1 mm)?
Fundamentally, the use of small particles is recommended for small defects (up to 2 dental alveoli) and for augmenting autogenous grafts. The large particles are recommended for large defects (> 2 dental alveoli, sinus lifts), however, preferences can vary from dentist to dentist.
2. Can Geistlich Bio-Oss Pen® also be used without membrane?
A membrane should be used in conjunction with Geistlich Bio-Oss® as a barrier against the ingrowth of soft tissue1. Native collagen membranes such as Geistlich Bio-Gide® also promote wound healing and increase therapeutic safety in the event of a postoperative wound dehiscence2,3. Clinicians should read the package insert prior to use.


  1. Gielkens PF, et al.: Clin Oral Implants Res 2008; 19: 516-21.
  2. Tal H, et al.: Clin Oral Implants Res 2008; 19: 295-302.
  3. Becker J, et al.: Clin Oral Implants Res 2009; 20(7): 742-49.
3. How much saline or blood is needed to moisten the Geistlich Bio-Oss Pen®?
0.5 cc Geistlich Bio-Oss Pen®: ~0.5 ml
1.0 cc Geistlich Bio-Oss Pen®: ~1.0 ml
1.5 cc Geistlich Bio-Oss Pen®: ~1.5 ml
4. How many Geistlich Bio-Oss Pen® delivery systems are needed for a sinus floor elevation?
Depending on the size of the defect, between 1.5 to 4 cc of Geistlich Bio-Oss® granules are needed, 3cc on average. This is equivalent to two 1.5cc Geistlich Bio-Oss Pen® with large granules or three 1cc Geistlich Bio-Oss Pen® with small granules.
5. Can the Geistlich Bio-Oss® granules be mixed with autologous bone in the Geistlich Bio-Oss Pen®?
No, Geisltich does not recommend mixing autologous bone with the Geistlich Bio-Oss® granules within the syringe.
6. Can the Geistlich Bio-Oss Pen® be re-sterilized?
No. If Geistlich Bio-Oss® is autoclaved, moisture can collect in the particles due to the high porosity of the product, which can change the hydrophilic properties. Moreover, Geistlich Bio-Oss® is not approved for re-sterilization. Re-sterilization under any circumstances is not recommended.
7. If the applicator tip is contaminated (e.g. has fallen on the floor) can it be re-used?
No. Discard and use a new Geistlich Bio-Oss Pen®.
8. Can separate applicator tips be ordered?
No. The applicator tips are not available separately.
9. Are other applicator tips (forms, length, diameter) available?
No. There are no other tips available.


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