HANSAmed Geistlich Bio-Gide

Geistlich Bio-Gide®

1. Why is a membrane necessary?
Alveolar bone regenerates best with a membrane designed for guided bone regeneration. The use of a membrane leads to increased bone as well as better quality bone compared to procedures that do not include a membrane.1


  1. Schwarz F, et al.: Clin Oral Impl Res 2008; 19(4): 402-15.
2. How long should a membrane function as a barrier in Guided Bone Regeneration?
Expert clinicians have estimated that a membrane used in Guided Bone Regeneration should maintain its barrier function until the provisional matrix and woven bone are present. Barrier duration is considered to be necessary for 7 to 14 days in most cases. Optimal barrier function now means that occlusiveness is maintained until the wound heals – a process which normally takes about 2 weeks.

Geistlich Bio-Gide® has proven to support bone regeneration on an equivalent level as membranes with a longer barrier function, with a reduction of complications during wound healing.1-3


  1. Tal H, et al.: Clin Oral Implants Res 2008; 19(5): 295-302.
  2. Becker J, et al.: Clin Oral Implants Res 2009; 20(7): 742-49.
  3. Schwarz F, et al.: Clin Oral Implants Res 2008; 19(4): 402-15.
3. How does Geistlich Bio-Gide® differ from other collagen membranes?
Geistlich Bio-Gide® is a membrane with a unique bilayer structure. It combines optimal bone formation with complication-free wound healing and predictable outcomes. The native collagen of Geistlich Bio-Gide® leads to significantly less soft tissue dehiscences compared to artificially cross-linked membranes.1 A significant number of scientific publications and proven long-term clinical success support the safety and efficacy of Geistlich Bio-Gide®.
  1. Tal H, et al.: Clin Oral Impl Res 2008; 19: 295-302.
  2. Becker J, et al.: Clin Oral Impl Res 2009; 20(7): 742-49.
  3. Schwarz F, et al.: Clin Oral Impl Res 2008; 19(4): 402-15.
4. Have inflammatory reactions been associated with Geistlich Bio-Gide®?
Inflammation is a possible complication, which may occur with any surgery. However, biocompatibility of Geistlich Bio-Gide® has been verified in numerous studies.
5. Is it possible to have an allergic reaction to Geistlich Bio-Gide®?
As Geistlich Bio-Gide® is made of collagen, allergic reactions and inflammatory tissue reactions cannot be excluded. However this is extremely rare.
6. What happens if the membrane is applied with the rough surface towards the soft tissue?
The bilayer structure of Geistlich BioGide® has a compact and porous surface. The compact layer of Geistlich Bio-Gide®exhibits higher cell occlusiveness than the rough, porous layer, preventing the downgrowth of epithelial cells. If the membrane is applied with the porous surface placed toward the soft tissue, integration of the bone cells may take place more slowly. However, it is not necessary to remove the membrane.
7. Can Geistlich Bio-Gide® be re-sterilized?
No. Autoclaving or hot-air sterilization irreversibly destroys the collagen structure. The physical properties of the membrane are changed and the consistency of the product becomes like parchment paper. In addition, the product is not approved for re-sterilization and therefore may not be used.
8. Does the membrane have to be fixed?
As Geistlich Bio-Gide® adheres very well to the defect, it is normally not necessary to utilize fixation screws or pins. However, fixation is possible if required.
9. How can Geistlich Bio-Gide® be used in extraction socket management for open healing?
Geistlich Bio-Gide® can be used submerged or in an open healing situation1 depending on the surgeon’s preference. The advantages of the secondary intention healing of Geistlich Bio-Gide® include the ability to perform a flapless surgery and the preservation of the mucogingival line.


  1. Cardaropoli D, et al.: Int J Periodontics Restorative Dent 2012, 32(4): 421-30.


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