About Ultracaine®

Ultracaine History

Ultracaine® is the original Articaine. This anesthetic drug was developed in the late 1970’s by a German company called Hoescht AG which is now part of SANOFI, one of the largest pharmaceutical companies in the world. Ultracaine was launched in Canada in 1983, and in 1999 distribution was taken over by HANSAmed. We are still at present the sole distributor of Ultracaine nationwide.

Ultracaine® is specifically designed for dentistry and provides clinicians with predictability, safety, and efficacy

HANSAmed Ultracaine DS
HANSAmed Ultracaine DS Forte

What makes Ultracaine® special? 

  • First Articaine in the market
  • Amide-type local anesthetic
  • Designed especially for dentistry
  • Has the unique feature of containing an additional ester group that is metabolized by enzymes in the blood and tissue reducing toxicity

Ultracaine®’s Structure 

Ultracaine® is an amide local anesthetic containing a vasoconstrictor and is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental procedures.

Ultracaine® has the shortest half-life of all anesthetic solutions. Due to the quick elimination from the bloodstream, Ultracaine®’s chemical structure allows it to be metabolized by blood esterases before reaching the liver. The 27-minute breakdown of Ultracaine to an inactive metabolite is related to a very low systemic toxicity and consequently to the possibility of repeated injections. Ultracaine® also has high lipid solubility which allows the anesthetic to diffuse better through soft tissue and bone. Articaine is the only local anesthetic to contain a thiophene ring, meaning it can be described as ‘thiophenic’; this conveys lipid solubility.

Ultracaine® Features & Benefits 

Each individual cartridge is manufactured aseptically and is latex-free. Ultracaine® is the only anesthetic that is packaged in a unique environmentally-friendly, all-cardboard packaging that is easy to recycle. Ultracaine® comes with unique features such as a white plunger for better contrast against the oral mucosa. The unique plunger is also embedded with a dimple to assist with successful aspiration. Along the colour-coded outer label of the 1.7 mL carpule is a measuring meter to help ensure the correct amount of anesthetic is being dispensed.

Ultracaine® is manufactured with the longest approved shelf-life by Health Canada for a local anesthetic solution with vasoconstrictor. Ultracaine® is manufactured with two epinephrine concentrations: 1:100,000 & 1:200,000 and is the only local anesthetic in North America that uses straight epinephrine in its formula. This is a unique feature of our product is evidence that all Articaine is not the same.

Ultracaine® is a rapidly growing anesthetic in the dental market and with 30+ years of experience, there have been zero recalls on the solution.


Call us at 1 800 363 2876 to book the order or click the button to buy now on iSHOP